The Israeli prime minister said Wednesday Yemen's Houthi militants will learn the lesson fellow Iran-backed militant groups like Hamas and Hezbollah learned from the Jewish state.

"Israel is striking the enemies and those who thought they will sever our lives here, so it will apply to everyone," Benjamin Netanyahu said on Wednesday.

"The Houthis too will learn what Hamas and Hezbollah and Assad’s regime and others learned, and even if it takes time this lesson will be learned across the Middle East," he added.

His comments came two days after his defense minister, Israel Katz, vowed to "behead" the Houthis' leaders in response to their ongoing missile and drone launches against Israel.

"These days, when the Houthi terrorist organization is firing missiles at Israel, I want to convey a clear message to them at the beginning of my remarks: We have defeated Hamas, we have defeated Hezbollah, we have blinded Iran's defense systems and damaged the production systems, we have toppled the Assad regime in Syria, we have dealt a severe blow to the axis of evil, and we will also deal a severe blow to the Houthi terrorist organization in Yemen, which remains the last to stand," Katz said.

"We'll severely cripple the Houthis, damage their strategic infrastructure, and we will behead their leaders – just as we did to Haniyeh, Sinwar and Nasrallah in Tehran, Gaza and Lebanon – we will do it in Hodeidah and Sana'a," Katz added.